Total syntheses of shizukaols A and E

Jian-Li Wu; Yin-Suo Lu; Bencan Tang; Xiao-Shui Peng

doi:10.1038/s41467-018-06245-7

Nature Communications (Oct 2018)

Total syntheses of shizukaols A and E

Jian-Li Wu,
Yin-Suo Lu,
Bencan Tang,
Xiao-Shui Peng

Affiliations

Jian-Li Wu: Department of Chemistry, and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong
Yin-Suo Lu: Department of Chemistry, and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong
Bencan Tang: Department of Chemical and Environmental Engineering, The University of Nottingham Ningbo China
Xiao-Shui Peng: Department of Chemistry, and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong

DOI: https://doi.org/10.1038/s41467-018-06245-7
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 7

Abstract

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Shizukaols, bioactive dimers naturally occurring in the Chloranthaceae family, possess a complex polycyclic framework with more than ten contiguous stereocenters. Here the authors report the total syntheses of shizukaols A and E achieved via a modified Diels–Alder reaction mimicking the biosynthetic pathway.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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