P176 ARTERIAL STIFFNESS AS A PART OF A GENERAL ABNORMALITY OF THE FIBROUS HEALING PROCESS

Abstract

Environment There seems to be a common abnormality of the healing process in several diseases as COPD, liver esteatosis, and arterial stiffening. Objective: To asses the association of frequency between liver esteatosis and aortic stiffness by means of c-f PWV in patients included in a CV prevention programme. Methods: 43 patients underwent a simultaneous evaluation including antropometry, biochemistry, cardiac, vascular and abdominal ultrasonography. Results: Mean age was 53,4 ± 11 y.o, 67% male, SBP 137 ± 17, DBP 87 ± 10 PP 50,3 ± 11 mmHg, BMi 29 ± 4. CVRF: HTN 74%, DLP 69%, DBT 7%, TBQ 28%, OBS 42%, OVWT 28%, SED 71%.CV Drugs: 63%. Nine (21%) presented abnormal PWV and esteatosis and 17 (39,5%) none of them. Whereas 4 (9,5%) presented abnormal PWV with normal liver and 13 (30%) the opposite. (Fisher NS, Cochran’s <.05). More information about LV mass and atherosclerotic burden is presented. Conclusion: In a group of p. in a Primary CV prevention programme there is a trend to a significative association between the presence or not of liver esteatosis and aortic stiffness. A wider investigation of fibrosis and the healing process in different tissues should be considered as a future research target.