Nature Communications (Jun 2020)

Pushing the boundaries of optoacoustic microscopy by total impulse response characterization

  • Markus Seeger,
  • Dominik Soliman,
  • Juan Aguirre,
  • Gael Diot,
  • Jakob Wierzbowski,
  • Vasilis Ntziachristos

DOI
https://doi.org/10.1038/s41467-020-16565-2
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 13

Abstract

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Characterizing the total impulse response (TIR) of photoacoustic microscopes has been challenging due to difficulties distributing appropriate point sources. Here, the authors present a method for 3D generation of spatially-distributed optoacoustic point sources and show that subsequent TIR correction results in improved image quality.