Unusual manifestation of synovial sarcoma: A rare case report with elevated beta HCG level

Elnaz Khosh, MD; Arya Kazemi, MD; Elahe Abbaspour, MD; Sanaz Vahdati, MD; Maryam Sadat Mirenayat, MD; Siavash Ghaderi-Sohi, MD; Sara Haseli, MD; Elham Askari, MD

Radiology Case Reports (Nov 2024)

Unusual manifestation of synovial sarcoma: A rare case report with elevated beta HCG level

Elnaz Khosh, MD,
Arya Kazemi, MD,
Elahe Abbaspour, MD,
Sanaz Vahdati, MD,
Maryam Sadat Mirenayat, MD,
Siavash Ghaderi-Sohi, MD,
Sara Haseli, MD,
Elham Askari, MD

Affiliations

Elnaz Khosh, MD: Department of Radiology, Zanjan University of Medical Sciences, Zanjan, Iran; Corresponding author.
Arya Kazemi, MD: Shahid Beheshti University of Medical Sciences, Tehran, Iran
Elahe Abbaspour, MD: Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran
Sanaz Vahdati, MD: Radiology Informatics Lab (RIL), Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
Maryam Sadat Mirenayat, MD: Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
Siavash Ghaderi-Sohi, MD: Kariminejad-Najmabadi Pathology & Genetics Center, Tehran, Iran
Sara Haseli, MD: Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
Elham Askari, MD: Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran; Corresponding author.

Journal volume & issue: Vol. 19, no. 11
pp. 5262 – 5267

Abstract

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Synovial sarcoma is a rare type of soft tissue sarcoma that typically arises in the lower extremities and rarely in the upper extremities. Here, we present an unusual case of a middle-aged man who complained of dyspnea, dry cough, and chest pain and was found to have a mass-like lesion on the ulnar side of his left wrist during physical examination. The patient also exhibited gynecomastia and had elevated β-human chorionic gonadotropin (βHCG) levels. Subsequent imaging and histopathological analysis of the wrist mass confirmed the diagnosis of synovial sarcoma with disseminated lung metastasis.This article aims to provide a comprehensive overview of the clinical and pathological characteristics of synovial sarcoma, highlight the importance of considering synovial sarcoma as a differential diagnosis in patients with abnormal hormonal assays, and emphasize the need for clinicians to be vigilant about any pathologic lesions existing on the upper extremity to avoid late diagnosis and the development of advanced cancerous diseases.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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