Green synthesis of pyrazole systems under solvent-free conditions

Abstract

In this paper, we offered a green, environment-friendly, novel and inexpensive method for the synthesis of a series of pyrazole derivatives. The reaction took place in the presence of tetrabutylammonium bromide, a commercially available organic ionic salt, at room temperature under solvent-free conditions. All products were confirmed by infrared radiation, nuclear magnetic resonance and elemental analysis. Yields of products were 75–86%.

Keywords

• Pyrazole systems
• 1,2-dibenzoylhydrazines
• green method
• solvent-free conditions
• tetrabutylammonium bromide