The use of nitric oxide in premature neonates: a 15-year retrospective chart review

Abstract

Aim: We aim to describe some characteristics of premature neonates which may predict response to inhaled nitric oxide (iNO). Methods: Neonates 1,000 g and older gestational age were more likely to respond to iNO therapy. Our findings also suggest that infants with PPROM may benefit from the use of iNO for respiratory distress. As a result, these findings support the individualized use of iNO in select premature infants whose premorbid characteristics deem them more likely to have a positive response.

Keywords

• inhaled nitric oxide
• premature rupture of membranes
• preterm infants
• pulmonary hypertension
• respiratory disease
• respiratory distress