Communications Medicine (Nov 2022)
Retrospective study of the immunogenicity and safety of the CoronaVac SARS-CoV-2 vaccine in people with underlying medical conditions
- Chunmei Li,
- Hanfang Bi,
- Zhenwang Fu,
- Ao Li,
- Na Wan,
- Jun Hu,
- Fan Yang,
- Tai-Cheng Zhou,
- Yupeng Liang,
- Wei Su,
- Tianpei Shi,
- Mei Yang,
- Rong Wang,
- Wanting Qin,
- Xuanjing Yu,
- Hong-Yi Zheng,
- Zumi Zhou,
- Yong-Tang Zheng,
- Jia Wei,
- Gang Zeng,
- Zijie Zhang,
- the Precise-CoVaccine study group
Affiliations
- Chunmei Li
- State Key Laboratory for Conservation and Utilization of Bio-resources and School of Life Sciences, Yunnan University
- Hanfang Bi
- State Key Laboratory for Conservation and Utilization of Bio-resources and School of Life Sciences, Yunnan University
- Zhenwang Fu
- Hainan Center for Disease Control and Prevention
- Ao Li
- State Key Laboratory for Conservation and Utilization of Bio-resources and School of Life Sciences, Yunnan University
- Na Wan
- State Key Laboratory for Conservation and Utilization of Bio-resources and School of Life Sciences, Yunnan University
- Jun Hu
- Outpatient department, The Affiliated Hospital of Yunnan University
- Fan Yang
- State Key Laboratory for Conservation and Utilization of Bio-resources and School of Life Sciences, Yunnan University
- Tai-Cheng Zhou
- Central Lab and Liver Disease Research Center, The Affiliated Hospital of Yunnan University
- Yupeng Liang
- Sinovac Biotech Co. Ltd.
- Wei Su
- State Key Laboratory for Conservation and Utilization of Bio-resources and School of Life Sciences, Yunnan University
- Tianpei Shi
- State Key Laboratory for Conservation and Utilization of Bio-resources and School of Life Sciences, Yunnan University
- Mei Yang
- State Key Laboratory for Conservation and Utilization of Bio-resources and School of Life Sciences, Yunnan University
- Rong Wang
- State Key Laboratory for Conservation and Utilization of Bio-resources and School of Life Sciences, Yunnan University
- Wanting Qin
- State Key Laboratory for Conservation and Utilization of Bio-resources and School of Life Sciences, Yunnan University
- Xuanjing Yu
- State Key Laboratory for Conservation and Utilization of Bio-resources and School of Life Sciences, Yunnan University
- Hong-Yi Zheng
- Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences
- Zumi Zhou
- State Key Laboratory for Conservation and Utilization of Bio-resources and School of Life Sciences, Yunnan University
- Yong-Tang Zheng
- Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences
- Jia Wei
- Central Lab and Liver Disease Research Center, The Affiliated Hospital of Yunnan University
- Gang Zeng
- Sinovac Biotech Co. Ltd.
- Zijie Zhang
- State Key Laboratory for Conservation and Utilization of Bio-resources and School of Life Sciences, Yunnan University
- the Precise-CoVaccine study group
- DOI
- https://doi.org/10.1038/s43856-022-00216-2
- Journal volume & issue
-
Vol. 2,
no. 1
pp. 1 – 11
Abstract
Li et al. evaluate the immunogenicity and safety of the CoronaVac inactivated COVID-19 vaccine in elderly patients with underlying medical conditions in China. Most patients show comparable neutralizing antibody and SARS-CoV-2-specific T cell responses to healthy controls, and no serious adverse effects are seen.