Case Reports in Obstetrics and Gynecology (Jan 2018)

Pregnancy Complications in a-Thalassemia (Hemoglobinopathy H): A Case Study

  • Marianna Politou,
  • Giorgos Dryllis,
  • Maria Efstathopoulou,
  • Serena Valsami,
  • Faidra-Evangelia Triantafyllou,
  • Athanasia Tsaroucha,
  • Antonios Kattamis,
  • Nikos F. Vlahos

DOI
https://doi.org/10.1155/2018/8532081
Journal volume & issue
Vol. 2018

Abstract

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Thalassemia intermedia (TI) is a clinical definition which represents a wide spectrum of thalassemia genotypes but mainly includes patients who do not require or only occasionally require transfusion. An uncommon case of a 32-year-old Greek woman, para 1, at the 22nd week + day 3 of gestation with thalassemia intermedia (she was splenectomized), where her pregnancy was complicated with portal vein thrombosis, splenic thrombosis, and partial HELLP, is described. This is a generally uncommon event in thalassemia intermedia. She had no transfusion as her hematologist consulted and she took anticoagulation therapy. Thus, we present for the first time in the literature a case of HbH a-thalassemia pregnant woman whose pregnancy was complicated with portal vein thrombosis, splenic vein thrombosis, and partial HELLP; she was treated with anticoagulation therapy and she had a successful outcome.