Nature Communications (Jan 2020)

Glycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both O-glycosides and nucleosides

  • Penghua Li,
  • Haiqing He,
  • Yunqin Zhang,
  • Rui Yang,
  • Lili Xu,
  • Zixi Chen,
  • Yingying Huang,
  • Limei Bao,
  • Guozhi Xiao

DOI
https://doi.org/10.1038/s41467-020-14295-z
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 10

Abstract

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O-glycosides and nucleosides are important biomolecules. Here, the authors developed a protocol for the synthesis of such molecules with a broad substrate scope using glycosyl ortho-(1-phenylvinyl)benzoates as glycosyl donors that allow for mild reaction conditions and high yields.