Biomarkers in Alzheimer’s disease

Abstract

Alzheimer’s disease (AD) is a progressive neurodegenerative disease. AD is the main cause of dementia worldwide and aging is the main risk factor for developing the illness. AD classical diagnostic criteria rely on clinical data. However, the development of a biological definition of AD using biomarkers that reflect the underling neuropathology is needed.

Keywords

• alzheimer’s disease
• β-amyloid
• blood
• cerebrospinal fluid
• cognitive deficit
• mild cognitive impairment
• neuroimaging