Comparison of two methods for evaluating lower urinary tract symptoms in cervical cancer patients following radical hysterectomy

Fang An; Sha Wang; Zhiqi Wang; Lingying Wu; Qiubo Lv; Aiming Lv; Hongwu Wen; Jinsong Han; Yumei Wu; Yunong Gao; Qing Liu; Sumei Wang; Hongxia Li; Luwen Wang; Yanlong Wang; Ruifang Wu; Huan Li; Xiuli Sun

Gynecology and Obstetrics Clinical Medicine (Jun 2021)

Comparison of two methods for evaluating lower urinary tract symptoms in cervical cancer patients following radical hysterectomy

Fang An,
Sha Wang,
Zhiqi Wang,
Lingying Wu,
Qiubo Lv,
Aiming Lv,
Hongwu Wen,
Jinsong Han,
Yumei Wu,
Yunong Gao,
Qing Liu,
Sumei Wang,
Hongxia Li,
Luwen Wang,
Yanlong Wang,
Ruifang Wu,
Huan Li,
Xiuli Sun

Affiliations

Fang An: Department of Obstetrics and Gynecology, Peking University People’s Hospital, Beijing, 100044, China; Beijing Key Laboratory of Female Pelvic Floor Disorders, Beijing, China; Female Pelvic Floor Disease Research Center, Peking University, Beijing, China; The Research Center of Female Pelvic Floor Dysfunction and Disease of Peking University People’s Hospital, Beijing, China
Sha Wang: Department of Obstetrics and Gynecology, Peking University People’s Hospital, Beijing, 100044, China; Beijing Key Laboratory of Female Pelvic Floor Disorders, Beijing, China; Female Pelvic Floor Disease Research Center, Peking University, Beijing, China; The Research Center of Female Pelvic Floor Dysfunction and Disease of Peking University People’s Hospital, Beijing, China
Zhiqi Wang: Department of Obstetrics and Gynecology, Peking University People’s Hospital, Beijing, 100044, China; Beijing Key Laboratory of Female Pelvic Floor Disorders, Beijing, China; Female Pelvic Floor Disease Research Center, Peking University, Beijing, China; The Research Center of Female Pelvic Floor Dysfunction and Disease of Peking University People’s Hospital, Beijing, China
Lingying Wu: Cancer Hospital Chinese Academy of Medical Sciences, Beijing, China
Qiubo Lv: Beijing Hospital, Beijing, China
Aiming Lv: Beijing Hospital, Beijing, China
Hongwu Wen: Peking University First Hospital, Beijing, China
Jinsong Han: Peking University Third Hospital, Beijing, China
Yumei Wu: Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing, China
Yunong Gao: Beijing Cancer Hospital & Beijing Institute for Cancer Research, Beijing, China
Qing Liu: Gansu Provincial Maternity and Child-care Hospital, Gansu, China
Sumei Wang: Beijing Chao-yang Hospital, Capital Medical University, Beijing, China
Hongxia Li: Beijing Shi Ji Tan Hospital, Beijing, China
Luwen Wang: The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China
Yanlong Wang: Xiamen Maternal and Child Health Hospital, Xiamen, China
Ruifang Wu: Peking University Shenzhen Hospital, Shenzhen, China
Huan Li: Peking University Shenzhen Hospital, Shenzhen, China
Xiuli Sun: Department of Obstetrics and Gynecology, Peking University People’s Hospital, Beijing, 100044, China; Beijing Key Laboratory of Female Pelvic Floor Disorders, Beijing, China; Female Pelvic Floor Disease Research Center, Peking University, Beijing, China; The Research Center of Female Pelvic Floor Dysfunction and Disease of Peking University People’s Hospital, Beijing, China; Corresponding author. Department of Obstetrics and Gynecology, Peking University People’s Hospital, Beijing, 100044, China.

Journal volume & issue: Vol. 1, no. 2
pp. 70 – 74

Abstract

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Objective: To compare the degree of agreement and consistency of urodynamic studies (UDS) with low urinary tract symptoms (LUTS) questionnaires for evaluating LUTS in cervical cancer patients following radical hysterectomy (RH) and pelvic lymphadenectomy. Methods: From January 2012 to March 2015, 204 cervical cancer patients who underwent RH in 13 hospitals were evaluated using the Incontinence Questionnaire-Female Lower Urinary Tract Symptoms (ICIQ-FLUTS) and the Overactive Bladder Symptom Score (OABSS). Urodynamic tests were also performed on these patients during the same period. Results: Study participants’ age ranged from 23 to 75 years, with a mean (standard deviation) of 48.0 ± 9.3 years. Using questionnaires, the prevalence of patients with LUTS symptoms, including storage symptoms, voiding symptoms, stress urinary incontinence (SUI) and overactive bladder (OAB) was 86.3%, 77.0%, 62.7%, 52.9% and 14.7%, respectively. For UDS, the corresponding prevalence was 89.7%, 70.1%, 66.7%, 46.6% and 13.2%, respectively. The diagnostic concordance of questionnaires and UDS for storage symptoms, voiding symptoms, SUI and OAB was 79.9%, 66.7%, 66.7%, 57.4% and 79.9%, respectively. For voiding symptoms, the correlation coefficient was 0.272, which was higher than that of storage symptoms, SUI and OAB. Conclusions: In cervical cancer patients who have undergone RH, there was a moderate degree of agreement between UDS and symptom questionnaires in evaluating LUTS, but the consistency was poor. Medical personnel should be adequately trained in UDS to ensure LUTS are adequately diagnosed in patients.

Published in Gynecology and Obstetrics Clinical Medicine

ISSN: 2097-0587 (Print); 2667-1646 (Online)
Publisher: BMJ Publishing Group
Country of publisher: United Kingdom
LCC subjects: Medicine: Gynecology and obstetrics
Website: https://gocm.bmj.com

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