Cholera Specific Prophylaxis in Modern Conditions

Abstract

Described is cholera epidemiological situation in the world and in the Russian Federation. One of the causes of its deterioration is pointed out to be the emergence, in the modern period, of altered Vibrio cholerae eltor variants with increased virulence, which displaced typical strains in many countries of Asia and Africa. Described are licensed oral cholera vaccines and their prophylactic efficiency. Considered is the WHO strategy in regard with oral cholera vaccines application in emergencies of different character. The prospects of new generation vaccines development are presented.

Keywords

• cholera
• altered eltor variant
• specific prophylaxis
• cholera vaccines