EPIDEMIOLOGICAL CHARACTERISTIC OF VIRAL HEPATITIS B AND C IN THE HEMODIALYSIS UNITS IN SAINT-PETERSBURG IN MODERN TIME. Part 1. Registration of hemo-contact viral hepatitis and serological markers of HBV and HCV infections in patients of hemodialysis unit

Abstract

Abstract. Hemo-contact viral hepatitis B and C is significant public health problem in hospitals and particularly in hemodialisys units. To define modern situation of the problem the retrospective study of viral hepatitis B and C registration in hemodialysis units in Saint-Petersburg in 1997–2007 as well as testing of 295 patients from four units for serological markers of hepatitis B and C (HBsAg, anti-HBs, anti-HBc, anti-HCV) have been conducted. It was determined that registration of hepatitis B in the study period was 5,2 cases per 1000 patients/per year, hepatitis C — 8,2 cases per 1000 patients/per year. These rates were significantly higher than in the total city population. The serological markers of ongoing or past HBV/HCV infection were revealed in 78,3 per 100 patients. Obtained results confirm intensive viral circulation in hemodialysis units. Additional study of transmission routes using molecular epidemiology techniques is required.

Keywords

• viral hepatitis b
• viral hepatitis c
• hemodialysis
• epidemiology
• serological markers