MRI of diffuse-type tenosynovial giant cell tumour in the knee: a guide for diagnosis and treatment response assessment

Abstract

Key Points TGCT is categorised according to its site of involvement and growth pattern. D-TGCT is characterised by irregular synovial proliferation infiltrating multiple synovial knee recesses. Systematic MRI approach is provided for preoperative and systemic treatment response assessment. An overview of synovial knee recesses guides the radiologist in assessing blind spots. Machine learning-based tumour segmentation may be applied to assess D-TGCT tumour volume in the near future, so that treatment response assessment can be quantified and improved by artificial intelligence.

Keywords

• Tenosynovial giant cell tumour
• Diffuse-type TGCT
• Magnetic resonance imaging
• Colony-stimulating factor 1
• 3D segmentation