Mitochondrial transplantation: the advance to therapeutic application and molecular modulation

James D. McCully; James D. McCully; Pedro J. del Nido; Pedro J. del Nido; Sitaram M. Emani; Sitaram M. Emani

doi:10.3389/fcvm.2023.1268814

Frontiers in Cardiovascular Medicine (Dec 2023)

Mitochondrial transplantation: the advance to therapeutic application and molecular modulation

James D. McCully,
James D. McCully,
Pedro J. del Nido,
Pedro J. del Nido,
Sitaram M. Emani,
Sitaram M. Emani

Affiliations

James D. McCully: Department of Cardiac Surgery, Boston Children’s Hospital, Boston, MA, United States
James D. McCully: Harvard Medical School, Boston, MA, United States
Pedro J. del Nido: Department of Cardiac Surgery, Boston Children’s Hospital, Boston, MA, United States
Pedro J. del Nido: Harvard Medical School, Boston, MA, United States
Sitaram M. Emani: Department of Cardiac Surgery, Boston Children’s Hospital, Boston, MA, United States
Sitaram M. Emani: Harvard Medical School, Boston, MA, United States

DOI: https://doi.org/10.3389/fcvm.2023.1268814
Journal volume & issue: Vol. 10

Abstract

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Mitochondrial transplantation provides a novel methodology for rescue of cell viability and cell function following ischemia-reperfusion injury and applications for other pathologies are expanding. In this review we present our methods and acquired data and evidence accumulated to support the use of mitochondrial transplantation.

Published in Frontiers in Cardiovascular Medicine

ISSN: 2297-055X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system
Website: https://www.frontiersin.org/journals/cardiovascular-medicine

About the journal

Abstract

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