A case report on smear-Positive pulmonary tuberculosis with neurofibromatosis type-1

Abstract

Neurofibromatosis (NF) is a group of disorders that is caused by a genetic mutation which is dominantly inherited neurogenetic disorder. They are of three types: NF1, NF2, and schwannomatosis. Out of these three, NF1 is the most common. NF1 mainly affects the skin, peripheral and central nervous system, bones, cardiovascular, and endocrine systems. Tuberculosis is a bacterial infection of the lung that is caused by Mycobacterium tuberculosis. It spreads by speaking, sneezing, and coughing in the air. Active pulmonary infections can spread to other people. Here, we represent a case of a 45-year-old male diagnosed with pulmonary tuberculosis (PTB) presenting with breathlessness, fever, loss of appetite, runny nose, nervousness, and dry cough. The patient had multiple swellings over the body with papules and nodules seen on different parts of the body. Cafe-au-lait macules were also present. After the all-over examination, the patient was diagnosed with smear-positive PTB with NF1.

Keywords

• cafe-au-lait macules
• neurofibromatosis type 1
• tuberculosis