LONG-TERM RESULTS OF THE VALVE-SAVING SURGERY IN MARFAN SYNDROME PATIENTS

Abstract

The main causes of mortality and morbidity in Marfan syndrome patients are cardiovascular complications. The Bentall DeBono operation for long time has been a gold standard treatment for this pathology.Aim. To present the obvious benefits of valve-saving surgery stimulating for saving of aorta valve (AoV) in dysplasia of connective tissue.Material and methods. A single-center retrospective analysis was done, of the results of valve-saving operations on the aorta root. All Marfan syndrome patients were included, who had undergone valve-saving operation on AoV in 2007-2015 y. As the valve-saving operation the David method was used, operation of reimplanting of aorta root into prosthesis and supracoronary prosthesing of ascending aorta.Results. Nine-year freedom from aortic regurgitation more 2 grade in long-term follow-up was 64%. As the a causes for development of aortic valve insufficiency were progressing degenerations of AoV. There were no cases of bleedings and endocarditis. Expected cumulative survival was 63%.Conclusion. Valve-saving operations are applicable in patients with the syndrome of connective tissue dysplasia. However, the worth of valve-saving operations in Marfan syndrome is questionable. Taken the known data, the studies demanded, with more number of patients and longer follow-up.

Keywords

• aorta
• aortic regurgitation
• valve-saving surgery
• marfan syndrome