Life (Jan 2023)

Resveratrol, Epigallocatechin Gallate and Curcumin for Cancer Therapy: Challenges from Their Pro-Apoptotic Properties

  • Adele Chimento,
  • Maria D’Amico,
  • Arianna De Luca,
  • Francesca Luisa Conforti,
  • Vincenzo Pezzi,
  • Francesca De Amicis

DOI
https://doi.org/10.3390/life13020261
Journal volume & issue
Vol. 13, no. 2
p. 261

Abstract

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Plant-derived bioactive compounds are gaining wide attention for their multiple health-promoting activities and in particular for their anti-cancer properties. Several studies have highlighted how they can prevent cancer initiation and progression, improve the effectiveness of chemotherapy, and, in some cases, limit some of the side effects of chemotherapy agents. In this paper, we provide an update of the literature on the anti-cancer effects of three extensively studied plant-derived compounds, namely resveratrol, epigallocatechin gallate, and curcumin, with a special focus on the anti-cancer molecular mechanisms inducing apoptosis in the major types of cancers globally.

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