Lipid Metabolism Profiles in Rheumatic Diseases

Weilin Chen; Weilin Chen; Weilin Chen; Qi Wang; Bin Zhou; Lihua Zhang; Honglin Zhu; Honglin Zhu; Honglin Zhu

doi:10.3389/fphar.2021.643520

Frontiers in Pharmacology (Apr 2021)

Lipid Metabolism Profiles in Rheumatic Diseases

Weilin Chen,
Weilin Chen,
Weilin Chen,
Qi Wang,
Bin Zhou,
Lihua Zhang,
Honglin Zhu,
Honglin Zhu,
Honglin Zhu

Affiliations

Weilin Chen: Department of Rheumatology, Xiangya Hospital, Central South University, Changsha, China
Weilin Chen: National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China
Weilin Chen: Provincial Clinical Research Center for Rheumatic and Immunologic Diseases, Xiangya Hospital, Changsha, China
Qi Wang: Department of Radiology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China
Bin Zhou: Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China
Lihua Zhang: Department of Rheumatology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China
Honglin Zhu: Department of Rheumatology, Xiangya Hospital, Central South University, Changsha, China
Honglin Zhu: National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China
Honglin Zhu: Provincial Clinical Research Center for Rheumatic and Immunologic Diseases, Xiangya Hospital, Changsha, China

DOI: https://doi.org/10.3389/fphar.2021.643520
Journal volume & issue: Vol. 12

Abstract

Read online

Rheumatic diseases are a group of chronic autoimmune disorders that involve multiple organs or systems and have high mortality. The mechanisms of these diseases are still ill-defined, and targeted therapeutic strategies are still challenging for physicians. Recent research indicates that cell metabolism plays important roles in the pathogenesis of rheumatic diseases. In this review, we mainly focus on lipid metabolism profiles (dyslipidaemia, fatty acid metabolism) and mechanisms in rheumatic diseases and discuss potential clinical applications based on lipid metabolism profiles.

Published in Frontiers in Pharmacology

ISSN: 1663-9812 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Therapeutics. Pharmacology
Website: http://journal.frontiersin.org/journals/pharmacology

About the journal

Abstract

Keywords