Frontiers in Pharmacology (Apr 2021)

Lipid Metabolism Profiles in Rheumatic Diseases

  • Weilin Chen,
  • Weilin Chen,
  • Weilin Chen,
  • Qi Wang,
  • Bin Zhou,
  • Lihua Zhang,
  • Honglin Zhu,
  • Honglin Zhu,
  • Honglin Zhu

DOI
https://doi.org/10.3389/fphar.2021.643520
Journal volume & issue
Vol. 12

Abstract

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Rheumatic diseases are a group of chronic autoimmune disorders that involve multiple organs or systems and have high mortality. The mechanisms of these diseases are still ill-defined, and targeted therapeutic strategies are still challenging for physicians. Recent research indicates that cell metabolism plays important roles in the pathogenesis of rheumatic diseases. In this review, we mainly focus on lipid metabolism profiles (dyslipidaemia, fatty acid metabolism) and mechanisms in rheumatic diseases and discuss potential clinical applications based on lipid metabolism profiles.

Keywords