Prevalence and predictors of dyslipidemia among HAART treated and HAART naive HIV positive clients attending Debre Tabor Hospital, Debre Tabor, Ethiopia
Anemut Tilahun,
Endeshaw Chekol,
Awgchew Behaile Teklemaryam,
Melaku Mekonnen Agidew,
Zelalem Tilahun,
Fitalew Tadele Admassu,
Nega Dagnaw,
Misganaw Asmamaw Mengstie,
Alebachew Amsalu,
Enyew Fenta Mengistu,
Yibeltal Akelew,
Tadesse Asmamaw,
Berihun Bantie
Affiliations
Anemut Tilahun
Department of Biomedical Sciences, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia; Corresponding author.
Endeshaw Chekol
Department of Biomedical Sciences, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia
Awgchew Behaile Teklemaryam
Department of Biomedical Sciences, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia
Melaku Mekonnen Agidew
Department of Biomedical Sciences, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia
Zelalem Tilahun
Department of Biomedical Sciences, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia
Fitalew Tadele Admassu
Department of Biomedical Sciences, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia
Nega Dagnaw
Department of Biomedical Sciences, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia
Misganaw Asmamaw Mengstie
Department of Biomedical Sciences, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia
Alebachew Amsalu
Department of Public Health, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia
Enyew Fenta Mengistu
Department of Biomedical Sciences, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia
Yibeltal Akelew
Department of Medical Laboratory, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia
Tadesse Asmamaw
Department of Biochemistry, College of Health Sciences, Gondar University, Gondar, Ethiopia
Berihun Bantie
Department of Adult Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia
Background: Highly active anti-retroviral therapy has been reported to be associated with a number of side effects in human immunodeficiency virus patients among which dyslipidemia isa common metabolic disorder. Methods: A Hospital based comparative cross-sectional study among 228 HIV positive patients was conducted from July to August 2020. Socio-demographic and clinical data were collected using structured questionnaires. Fasting venous blood sample was collected and analyzed for Lipid profiles. EDTA sample was analyzed for CD4+ T cell determination. Anthropometric measurement was done. Data were analyzed using SPSS version 22. Independent t-test was done. Logistic and binary regression was done. Result: A total of 228 HIV patients were enrolled in the study. Prevalence of dyslipidemia in HAART naive and HAART treated patients was 61 (53.5%) and 84 (73.7%), respectively. The prevalence of Total Cholesterol ≥200 mg/dl was 50% and 30%; High density lipoprotein cholesterol 25 kg/m2 (AOR = 1.92, 95% C.I: 1.20–4.81) were identified as determinants of dyslipidemia. Conclusion: The mean value of lipid profile was significantly higher among HAART treated as compared to those HAART naive HIV positive clients.
