Nature Communications (Jan 2017)

Hollow boron nitride nanospheres as boron reservoir for prostate cancer treatment

  • Xia Li,
  • Xiupeng Wang,
  • Jun Zhang,
  • Nobutaka Hanagata,
  • Xuebin Wang,
  • Qunhong Weng,
  • Atsuo Ito,
  • Yoshio Bando,
  • Dmitri Golberg

DOI
https://doi.org/10.1038/ncomms13936
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 12

Abstract

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Use of soluble boron compounds in prostate cancer therapy is hampered by their short half-life time and low effectiveness. Here, the authors show that boron nitride nanospheres with controlled boron release can reduce proliferation of prostate cancer cells and inhibit tumour growth in animal models.