Эпидемиология и вакцинопрофилактика (Feb 2016)

Vaccinal prevention of Tick-Borne Encephalitis in chelyabinsk Region: Dynamics of Vaccination, population Immunity, Analysis of TBE cases in Vaccinated persons

  • S. V. Luchinina,
  • A. I. Semenov,
  • O. N. Stepanova,
  • V. V. Pogodina,
  • S. G. Gerasimov,
  • M. S. Shcherbinina,
  • L. I. Kolesnikova,
  • T. A. Suslova

DOI
https://doi.org/10.31631/2073-3046-2016-15-1-67-76
Journal volume & issue
Vol. 15, no. 1
pp. 67 – 76

Abstract

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The Chelyabinsk Region (Southern Urals) is high endemic territory. The TBE incidence is 3.57 ± 1.7 per 100 000 of population. A level of vaccination against TBE increased from 0.3 to 34.8% in 1999 - 2013. Specific immunity of population in 35.9% is connected with vaccination, in 64.1% with natural immunity consequently latent contact with TBE virus. Dynamics of vaccinal prevention, increasing of population immunity in different landscapes, and in different age groups were studied. 77.7% of TBE patients did not vaccinated, 18.2% received of specific immunoglobulin at postexposition and 3.7% persons were vaccinated. Unusual lethal case in patient, who received 8 doses of vaccine is analysed in this article.

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