Effect of some feed additives against toxicity induced by aflatoxin contaminated diet in broiler

Abstract

The effects of the Saccharomyces cerevisiae (SC) and Fructooligosaccharide (FOS) on body weight, feed conversion, body weight gain, and immune response was investigated in broiler fed on aflatoxin (AF). A total number of 180 one day old broiler chickens (Hubbard classic) were randomly distributed into 6 experimental groups; G1: control (basal diet), G2: (basal diet + SC 2%), G3: (basal diet + FOS 0.25%), G4: (basal diet + AF100μg), G5: (basal diet + AF100μg + SC 2%), G6: (basal diet + AF100μg + FOS 0.25). The weight range, feed conversion, body weight gain and humoral immunity of birds were evaluated. Results of (G2) and (G3) show a significant (P<0.05) increase weight range, body weight gain, fed conversion ratio, and the antibody titers in compare to control, while the AF contaminated diet (G4) showed a decrease in body weight gain, feed conversion ratio and the antibody titers against Newcastle disease virus. Aflatoxin groups treated with 2% Saccharomyces cerevisiae (G5) and 0.25% fructooligosaccharide (G6) show increased in the broilers performance value and humoral immune response of broilers vaccinated against Newcastle virus disease as compared to the aflatoxin group (G4). In conclusion, the addition of Saccharomyces cerevisiae and fructooligosaccharide had a beneficial effect on broilers health and can minimize the effect of aflatoxin on broiler performance and immunity.