Cancer Reports (Aug 2022)

A case report of prostate cancer with leptomeningeal metastasis

  • Mansoureh Dehghani,
  • Babak PeyroShabany,
  • Ramin Shahraini,
  • Danial Fazilat‐Panah,
  • Fateme Hashemi,
  • James S. Welsh,
  • Seyed Alireza Javadinia

DOI
https://doi.org/10.1002/cnr2.1463
Journal volume & issue
Vol. 5, no. 8
pp. n/a – n/a

Abstract

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Abstract Background Prostate cancer is the most prevalent cancer in men. However, leptomeningeal involvement by prostate carcinoma is a rare event. Case Here, we report a 69‐year‐old patient with castration‐resistant metastatic prostate cancer who presented with headache and ataxia. Brain MRI revealed a huge invasive interaxial mass at right occipital lobe with diffuse thickening and enhancement of meninges, the arachnoid, and the pia mater, and he was diagnosed with leptomeningeal carcinomatosis. The patient received whole brain radiotherapy. Conclusion Despite the fact that brain and leptomeningeal metastases are not very common in patients with prostate cancer, signs and symptoms of nervous system disorders should be assessed carefully, and consideration of such unusual metastases must be considered.

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