Biology (Aug 2021)

The Distribution and Prevalence of High-Risk HPV Genotypes Other than HPV-16 and HPV-18 among Women Attending Gynecologists’ Offices in Kazakhstan

  • Gulzhanat Aimagambetova,
  • Aisha Babi,
  • Alpamys Issanov,
  • Sholpan Akhanova,
  • Natalya Udalova,
  • Svetlana Koktova,
  • Askhat Balykov,
  • Zhanna Sattarkyzy,
  • Zhuldyz Abakasheva,
  • Azliyati Azizan,
  • Chee Kai Chan,
  • Torgyn Issa

DOI
https://doi.org/10.3390/biology10080794
Journal volume & issue
Vol. 10, no. 8
p. 794

Abstract

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Cervical cancer represents a great burden to public health of women. This study aimed to obtain a nationwide genotyping survey and analysis of high risk-HPV including those that are caused by HPV types other than HPV-16 and HPV-18, among women in Kazakhstan. This study was conducted based on the collection of survey and cervical swabs of 1645 women across the country. The samples were genotyped for high-risk HPV types based on real-time PCR methods. Collected data was analyzed with the focus on high-risk HPV types other than HPV-16 and -18. Infection was present in 22% of women who participated in the study. The most prevalent types were HPV-31 among single infections and HPV-68 among multiple infections. Conclusively, despite the lack of attention high-risk HPV types beyond HPV-16 and -18 get in attempts of cervical cancer prevention in Kazakhstan, their prevalence is high and plays a large role in cervical cancer epidemiological situation.

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