COVID-19: Molecular and Cellular Response

Shamila D. Alipoor; Esmaeil Mortaz; Esmaeil Mortaz; Hamidreza Jamaati; Payam Tabarsi; Hasan Bayram; Mohammad Varahram; Ian M. Adcock; Ian M. Adcock

doi:10.3389/fcimb.2021.563085

Frontiers in Cellular and Infection Microbiology (Feb 2021)

COVID-19: Molecular and Cellular Response

Shamila D. Alipoor,
Esmaeil Mortaz,
Esmaeil Mortaz,
Hamidreza Jamaati,
Payam Tabarsi,
Hasan Bayram,
Mohammad Varahram,
Ian M. Adcock,
Ian M. Adcock

Affiliations

Shamila D. Alipoor: Molecular Medicine Department, Institute of Medical Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran
Esmaeil Mortaz: Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Esmaeil Mortaz: Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Hamidreza Jamaati: Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
Payam Tabarsi: Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Hasan Bayram: Department of Pulmonary Medicine, Koc University School of Medicine, Koc University Research Center for Translational Medicine (KUTTAM), Istanbul, Turkey
Mohammad Varahram: Mycobacteriology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
Ian M. Adcock: National Heart and Lung Institute, Imperial College London and the NIHR Imperial Biomedical Research Centre, London, United Kingdom
Ian M. Adcock: Priority Research Centre for Asthma and Respiratory Disease, Hunter Medical Research Institute, University of Newcastle, Newcastle, NSW, Australia

DOI: https://doi.org/10.3389/fcimb.2021.563085
Journal volume & issue: Vol. 11

Abstract

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In late December 2019, a vtiral pneumonia with an unknown agent was reported in Wuhan, China. A novel coronavirus was identified as the causative agent. Because of the human-to-human transmission and rapid spread; coronavirus disease 2019 (COVID-19) has rapidly increased to an epidemic scale and poses a severe threat to human health; it has been declared a public health emergency of international concern (PHEIC) by the World Health Organization (WHO). This review aims to summarize the recent research progress of COVID-19 molecular features and immunopathogenesis to provide a reference for further research in prevention and treatment of SARS coronavirus2 (SARS-CoV-2) infection based on the knowledge from researches on SARS-CoV and Middle East respiratory syndrome-related coronavirus (MERS-CoV).

Published in Frontiers in Cellular and Infection Microbiology

ISSN: 2235-2988 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Science: Microbiology
Website: http://www.frontiersin.org/Cellular-and-Infection-Microbiology

About the journal

Abstract

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