NEW PRODUCTS OF MICROBIOLOGICAL TRANSFORMATION OF SCLAREOL: CHARACTERISTICAL AND BIOLOGICAL ACTIVITY

Abstract

For the first time, the active strains of local micro fungus were selected, responsible for the transformation of sclareol molecule at the peripheral level of oxidation-reduction reactions have been selected. The speed of biodegradation of sclareol and the optimal conditions for preparative gathering of the precious metabolites of sclareol by the active fungus of ggAspergillus and Penicillium have been thoroughly investigated. There were obtained new products of the sclareol biotransformation, with activity against some phytopathogens. The physiological and biochemical characteristics of active strains of Penicillium sp.176, Aspergillus sp. 120 were formulated, with their further identification; the strains Penicillium camemberti CNM-FP-03 and Aspergillus alliaceus CNM-FA-01 were identified and deposited in the NCNM as the strains of microorganisms capable to the transformation of sclareol.

Keywords

• біотрансформація
• лабдановий дитерпеноїд склареол
• мiкрoмiцети
• penicillium sp
• aspergillus sp