Frontiers in Oncology (May 2024)

Case report: Isolated oligometastatic disease of the prostate from a primary lung adenocarcinoma

  • Josette M. Kamel,
  • Simran Arjani,
  • Kateryna Fedorov,
  • Fnu Sapna,
  • Jinrong Cheng,
  • Ioannis Mantzaris

DOI
https://doi.org/10.3389/fonc.2024.1394168
Journal volume & issue
Vol. 14

Abstract

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Secondary prostate cancer typically occurs from direct seeding of a renal or bladder tumor. Metastasis via hematogenous spread is exceedingly rare and is typically identified incidentally at autopsy. This report describes a 72-year-old male with lung adenocarcinoma initially staged as Stage IA2 who developed oligometastatic disease of the prostate. He was initially treated with radiation therapy and was found to have a hypermetabolic focus in the prostate gland during surveillance PET/CT imaging 6 months following treatment. Subsequent biopsy revealed metastatic lung adenocarcinoma in 6/6 core samples, leading to diagnosis of oligometastatic disease of the prostate. To our knowledge, this is the first report of isolated oligometastatic disease to the prostate from a primary lung adenocarcinoma.

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