Craniopharyngioma (CP) is a rare tumor accounting for <1% of all primary central nervous system (CNS) tumors. We herein report a case of a 2.5 years old male child diagnosed with supra-sellar tumor on prenatal ultrasound. Histologically, the tumor had tooth enamel like structures, one of the rarest finding in the literature. This case from Pakistan is hereby reported as a seventh such case world-wide. Our patient is a rare presentation of an antenatal diagnosis of CP with World Health Organization (WHO) grade I.
