Nature Communications (Feb 2020)
Optogenetic engineering to probe the molecular choreography of STIM1-mediated cell signaling
Abstract
Optogenetic tools have been used to control cellular behaviours but their use to probe structure-function relations of signalling proteins are underexplored. Here the authors engineer optogenetic modules into STIM1 to dissect molecular details of STIM1-mediated signalling and control various cellular events.