Prediction Of Low Birth Weight Using Low Glucose Challenge Test In Pregnant Women

Abstract

Background: We conducted this study To find relationship between maternal glucose challenge test (GCT) levels and fetal body weight (BW). Materials and Methods: We analyzed five hundred women with singleton pregnancy, who had GCT at 24-28 week during pregnancy. All of them had no history of hypertension and diabetes mellitus or other medical disease before pregnancy or during previous pregnancy, and all of them had weight gain appropriate with their pre pregnancy body mass index (BMI). Also nobody had history of drug abuse or smoking. In this descriptive–analytic survey, maternal age, gravidity, BMI,GCT level ,gestational age (GA) , sex of neonate, rout of delivery , newborn weight and apgar score were evaluated .The student’s T-test and logistic regression were used for statistical analysis. We used Pearson coefficient and receiver operating characteristic (ROC) curve and chi-square test for determination GCT threshold. Results: We found rate of small for gestational age (SGA) in newborns statistically was significant, who their maternal GCT level was ≤ 80mg/dl, P value: 0/018, specificity 89%, sensitivity 58% and confidence interval: 95% (0/162-0/545). Conclusion: Low GCT level has association with SGA and can be used as a predictive test and may be an indication for dietary intervention.

Keywords

• Glucose challenge test (GCT)
• small for gestational age (SGA)
• neonate’s weight
• large for gestational age
• appropriate for gestational age