Preparation and Diagnosis of Pyrimidines Derivatives by Conventional And Microwave Ways.

Abstract

This work includes synthesis and characterization of new derivatives of pyrimidine (R. or Ar. -1, 2, 3, 4-tetrahydropyrimidin-5-yl) ethan-1-one), via the reaction of acetyl acetone with different aldehydes and guanidine hydrochloride. Using absolute ethanol as a solvent .This mixture was refluxed for (6– 20) hrs.at pH 6 we prepared .The same derivatives of pyrimidine were prepared in microwave way. This compounds were prepared characterized by melting point, FT-IR , UV-Vis and some of the with 1H-NMR and 13C-NMR spectroscopy .

Keywords

• preparation
• diagnosis
• pyrimidines
• conventional
• microwave ways