The role of saline nasal sprays or drops in nasal hygiene: a review of the evidence and clinical perspectives

Abstract

Background: This article provides, for the first time, a comprehensive view on everyday practice and evidence-based advice on the regular use of saline nasal sprays or drops to support nasal function and to help protect from airborne pollutants, pollens and viruses. Method: An extensive literature search was conducted with PubMed, Google Scholar and national healthcare databases to identify and summarise the evidence available to date on the role of saline nasal sprays or drops in nasal hygiene. Clinical perspectives from international respiratory specialists were included. Results: Following the PubMed searches, twenty-three articles were assessed in adults and children using isotonic or hypertonic saline nasal sprays and drops, including five systematic reviews and 11 randomised controlled trials. Six national clinical guidance documents were included from the other database searches to give a total of 29 articles. The findings support that regular, daily use of saline nasal sprays or drops could provide relief from nasal symptoms in adults and children with upper respiratory tract infections or allergic rhinitis; future studies are expected to demonstrate benefit following air pollutant exposure. No serious adverse events were reported. National guidance recommends daily nasal hygiene with saline sprays and drops, some from infancy. Conclusion: Regular, daily use of saline nasal spray or drops could reduce the effects of noxious stimuli in the nose, helping to support respiratory health.

Keywords

• air pollution
• nasal hygiene
• pollen
• saline nasal sprays or drops
• respiratory viruses