Wellcome Open Research (Sep 2022)
Revealing the extent of the first wave of the COVID-19 pandemic in Kenya based on serological and PCR-test data [version 3; peer review: 2 approved, 1 approved with reservations]
- Sophie Uyoga,
- Ambrose Agweyu,
- Rabia Aziza,
- Edwine Barasa,
- Benjamin Tsofa,
- Philip Bejon,
- Edward Otieno,
- Morris Ogero,
- John Ojal,
- Vincent Were,
- Samuel P. C. Brand,
- Ivy K. Kombe,
- Emelda A. Okiro,
- George M. Warimwe,
- Caroline Mburu,
- J. Anthony G. Scott,
- Ifedayo M. O. Adetifa,
- Charles N. Agoti,
- Lynette I. Ochola-Oyier,
- Patrick Amoth,
- Kadondi Kasera,
- Rashid Aman,
- Mercy Mwangangi,
- Matt J. Keeling,
- Wangari Ng’ang’a,
- D. James Nokes
Affiliations
- Sophie Uyoga
- ORCiD
- Kenya Medical Research Institute - Wellcome Trust Research programme, Kilifi, Kenya
- Ambrose Agweyu
- Kenya Medical Research Institute - Wellcome Trust Research programme, Kilifi, Kenya
- Rabia Aziza
- The Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research (SBIDER), University of Warwick, Coventry, UK
- Edwine Barasa
- Health Economics Research Unit, Kenya Medical Research Institute - Wellcome Trust Research Programme, Nairobi, Kenya
- Benjamin Tsofa
- ORCiD
- Kenya Medical Research Institute - Wellcome Trust Research programme, Kilifi, Kenya
- Philip Bejon
- ORCiD
- Kenya Medical Research Institute - Wellcome Trust Research programme, Kilifi, Kenya
- Edward Otieno
- ORCiD
- Health Economics Research Unit, Kenya Medical Research Institute - Wellcome Trust Research Programme, Nairobi, Kenya
- Morris Ogero
- ORCiD
- Health Economics Research Unit, Kenya Medical Research Institute - Wellcome Trust Research Programme, Nairobi, Kenya
- John Ojal
- Kenya Medical Research Institute - Wellcome Trust Research programme, Kilifi, Kenya
- Vincent Were
- Health Economics Research Unit, Kenya Medical Research Institute - Wellcome Trust Research Programme, Nairobi, Kenya
- Samuel P. C. Brand
- ORCiD
- The Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research (SBIDER), University of Warwick, Coventry, UK
- Ivy K. Kombe
- Kenya Medical Research Institute - Wellcome Trust Research programme, Kilifi, Kenya
- Emelda A. Okiro
- ORCiD
- Population Health Unit, Kenya Medical Research Institute - Wellcome Trust Research programme, Nairobi, Kenya
- George M. Warimwe
- ORCiD
- Kenya Medical Research Institute - Wellcome Trust Research programme, Kilifi, Kenya
- Caroline Mburu
- Kenya Medical Research Institute - Wellcome Trust Research programme, Kilifi, Kenya
- J. Anthony G. Scott
- Kenya Medical Research Institute - Wellcome Trust Research programme, Kilifi, Kenya
- Ifedayo M. O. Adetifa
- ORCiD
- Kenya Medical Research Institute - Wellcome Trust Research programme, Kilifi, Kenya
- Charles N. Agoti
- ORCiD
- Kenya Medical Research Institute - Wellcome Trust Research programme, Kilifi, Kenya
- Lynette I. Ochola-Oyier
- Kenya Medical Research Institute - Wellcome Trust Research programme, Kilifi, Kenya
- Patrick Amoth
- Ministry of Health, Government of Kenya, Nairobi, Kenya
- Kadondi Kasera
- Ministry of Health, Government of Kenya, Nairobi, Kenya
- Rashid Aman
- Ministry of Health, Government of Kenya, Nairobi, Kenya
- Mercy Mwangangi
- Ministry of Health, Government of Kenya, Nairobi, Kenya
- Matt J. Keeling
- ORCiD
- The Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research (SBIDER), University of Warwick, Coventry, UK
- Wangari Ng’ang’a
- Presidential Policy & Strategy Unit, The Presidency, Government of Kenya, Nairobi, Kenya
- D. James Nokes
- ORCiD
- Kenya Medical Research Institute - Wellcome Trust Research programme, Kilifi, Kenya
- Journal volume & issue
-
Vol. 6
Abstract
Policymakers in Africa need robust estimates of the current and future spread of SARS-CoV-2. We used national surveillance PCR test, serological survey and mobility data to develop and fit a county-specific transmission model for Kenya up to the end of September 2020, which encompasses the first wave of SARS-CoV-2 transmission in the country. We estimate that the first wave of the SARS-CoV-2 pandemic peaked before the end of July 2020 in the major urban counties, with 30-50% of residents infected. Our analysis suggests, first, that the reported low COVID-19 disease burden in Kenya cannot be explained solely by limited spread of the virus, and second, that a 30-50% attack rate was not sufficient to avoid a further wave of transmission.