Проблемы особо опасных инфекций (Apr 2008)

Possibility to Obtain Anti-Athrax Human Immunoglobulin for Intravenous Injection

  • V. Yu. Dolmatov,
  • A. V. Drobkova,
  • A. G. Lyutov,
  • O. V. Mal’tseva,
  • A. N. Shevtsov,
  • D. V. Borovskoy,
  • G. D. Yelagin,
  • M. V. Karpova,
  • O. A. Vershinina,
  • E. A. Blinova,
  • S. L. Sharygin

DOI
https://doi.org/10.21055/0370-1069-2008-2(96)-39-42
Journal volume & issue
Vol. 0, no. 2(96)
pp. 39 – 42

Abstract

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For the first time specific Ig was obtained from blood plasma of donors immunized by combined anthrax vaccine. This Ig conforms to quality standards for intravenous immunoglobulins and includes antibodies to Bacillus anthracis protective antigen in titer 1:1600 - 1:3200. Therapeutic and prophylactic efficacy of experimental-production series of preparation was demonstrated in experiments with animals.

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