Diagnostics (Apr 2023)

Chronic Complete Distal Aortic Occlusion and Pulmonary Embolism—Atypical Antiphospholipid Syndrome?

  • Simona Caraiola,
  • Laura Voicu,
  • Dragoș Cașu,
  • Elena Armășoiu,
  • Claudia Oana Cobilinschi,
  • Emilian Mihai,
  • Răzvan Adrian Ionescu

DOI
https://doi.org/10.3390/diagnostics13071346
Journal volume & issue
Vol. 13, no. 7
p. 1346

Abstract

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Complete aortic occlusion is a rare pathology with various possible etiologies. According to current data, it is most frequently caused by atherosclerosis. However, thrombosis or vasculitis could also be involved. We present the case of a 42-year-old female with chronic complete distal aortic occlusion, associated pulmonary embolism and positive antiphospholipid antibodies. The patient had an obstetric history suggestive of antiphospholipid syndrome (APS). She presented with typical intermittent claudication symptoms persisting for approximately five years at the time of admission. Arteriography revealed complete infrarenal aortic occlusion and the presence of collateral arteries. Aortoiliac bypass surgery was performed. This case emphasizes an unusual, yet possible, etiology of chronic aortic occlusion—most probably, combining atherosclerosis and chronic thrombosis—in a relatively young patient, in which the diagnosis was significantly delayed due to the peculiar association of traits.

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