Antifertility effects of furazolidone in Adult male rats

Abstract

Although various contraceptive methods and medications have been devised so far,there is no ideal male contraceptive agent,free from side effects and without adverse effects on secondary sexual characterestics and sexual behaviour.in this study the antifertility effects of furazolidone on the process of spermatogenesis in adelt male rats have been evaluated.the results indicate that this drug significantly decreases daily sperm production(DSP),motility,epididymal sperm reserve(ESR) and therefore decreases the infertility indices.consequently this drug can be used as a lead compound in the synthesis of male contraceptive druge.

Keywords

• male contraceptive agent
• furazolidone
• antifertility