Rambam Maimonides Medical Journal (Oct 2022)

CRISPR Technology: A Jewish Legal Perspective

  • John D. Loike,
  • Rabbi Tzvi Flaum

DOI
https://doi.org/10.5041/RMMJ.10487
Journal volume & issue
Vol. 13, no. 4
p. e0029

Abstract

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Clustered regularly interspaced short palindromic repeats (CRISPR) gene editing is an innovative and potentially game-changing biotechnology that can potentially reverse DNA mutations in a tissue-specific manner. In addition, CRISPR is being targeted for xenotransplantation, for increasing human longevity, in animal breeding, and in plant science. However, there are many ethical challenges that emerge from CRISPR technology. This article discusses several positions that relate to these ethical challenges from a Jewish legal perspective. In addition, we present several other applications of CRISPR technology that lack a defined Jewish legal precedent and require rabbinical scholars to address and resolve them in the future.

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