Medicina (Dec 2022)

A Rare Kimura’s Disease in the Oral Cavity with Severe Sleep Apnea: Case Report and Literature Review

  • Xiaoyue Lei,
  • Dan Yu,
  • Xiaoyan Feng,
  • Yiyang Shen,
  • Huiyong Zhu

DOI
https://doi.org/10.3390/medicina58121810
Journal volume & issue
Vol. 58, no. 12
p. 1810

Abstract

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Kimura’s disease (KD) is a rare chronic inflammatory disorder that commonly occurs in Asian males. It mainly presents as painless subcutaneous masses or lymphadenopathy in the head and neck region. The incidence of KD in the oral cavity is quite rare. We reported a rare case of a 53-year-old male who had KD in his soft palate, hard palate and bilateral tonsils associated with severe sleep apnea. This patient underwent radiotherapy and exhibited a good response to the treatment. Throughout the 12-month follow-up period, the patient’s condition remained satisfactory. Of the other 14 reviewed cases of KD in the oral cavity, the lesions can occur in the buccal mucosa, hard and soft palate, and mouth floor with specific clinical features. We further summarized their manifestations and treatments in order to guide the future identification and management of KD with lesions in the oral cavity.

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