Circulating serum sVCAM-1 concentration in advanced ovarian cancer patients: correlation with concentration in ascites

Abstract

Background. Vascular cell adhesion molecule-1 (VCAM-1) is associated with ovarian cancer progression but the origin of its soluble form (sVCAM-1) in serum is not well investigated. The purpose of this study was to elucidate whether the concentration of sVCAM-1 in serum correlates with the concentration in ascites, that represents local tumour environment, and with systemic inflammation, various clinicopathological characteristics, and patient outcome.

Keywords

• svcam-1
• ovarian cancer
• flow cytometry