Nature Communications (Jun 2020)
Organic NIR-II molecule with long blood half-life for in vivo dynamic vascular imaging
- Benhao Li,
- Mengyao Zhao,
- Lishuai Feng,
- Chaoran Dou,
- Suwan Ding,
- Gang Zhou,
- Lingfei Lu,
- Hongxin Zhang,
- Feiya Chen,
- Xiaomin Li,
- Guangfeng Li,
- Shichang Zhao,
- Chunyu Jiang,
- Yan Wang,
- Dongyuan Zhao,
- Yingsheng Cheng,
- Fan Zhang
Affiliations
- Benhao Li
- Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials and iChem, Fudan University
- Mengyao Zhao
- Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials and iChem, Fudan University
- Lishuai Feng
- Department of Radiology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital
- Chaoran Dou
- Department of Ultrasound in Medicine, Shanghai Institute of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital
- Suwan Ding
- Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials and iChem, Fudan University
- Gang Zhou
- Lab of Advanced Materials & Department of Macromolecular Science, Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University
- Lingfei Lu
- Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials and iChem, Fudan University
- Hongxin Zhang
- Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials and iChem, Fudan University
- Feiya Chen
- Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials and iChem, Fudan University
- Xiaomin Li
- Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials and iChem, Fudan University
- Guangfeng Li
- Lab of Advanced Materials & Department of Macromolecular Science, Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University
- Shichang Zhao
- Department of Orthopedics, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University
- Chunyu Jiang
- Department of Radiology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital
- Yan Wang
- Department of Ultrasound in Medicine, Shanghai Institute of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital
- Dongyuan Zhao
- Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials and iChem, Fudan University
- Yingsheng Cheng
- Department of Radiology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital
- Fan Zhang
- Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials and iChem, Fudan University
- DOI
- https://doi.org/10.1038/s41467-020-16924-z
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 11
Abstract
Optical bioimaging in the second near-infrared (NIR-II, 1000–1700 nm) window exhibits abundant advantages. Here the authors report an organic NIR-II molecule with long blood circulation half-life time for continuous real-time monitoring of dynamic vascular processes.