Enhanced germline stem cell longevity in Drosophila diapause

Sreesankar Easwaran; Matthew Van Ligten; Mackenzie Kui; Denise J. Montell

doi:10.1038/s41467-022-28347-z

Nature Communications (Feb 2022)

Enhanced germline stem cell longevity in Drosophila diapause

Sreesankar Easwaran,
Matthew Van Ligten,
Mackenzie Kui,
Denise J. Montell

Affiliations

Sreesankar Easwaran: Molecular, Cellular, and Developmental Biology Department, University of California
Matthew Van Ligten: Molecular, Cellular, and Developmental Biology Department, University of California
Mackenzie Kui: Molecular, Cellular, and Developmental Biology Department, University of California
Denise J. Montell: Molecular, Cellular, and Developmental Biology Department, University of California

DOI: https://doi.org/10.1038/s41467-022-28347-z
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 16

Abstract

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Drosophila enter adult reproductive diapause in low temperatures and short day, halting ovarian development yet preserving fertility. Here the authors show that ovarian arrest in diapause is distinct from other stress responses and that despite DNA damage and decreased division, germline stem cells recover.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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