Endocrine Regulations (Jul 2020)

The cytochrome 11B2 aldosterone synthase gene rs1799998 single nucleotide polymorphism determines elevated aldosterone, higher blood pressure, and reduced glomerular filtration, especially in diabetic female patients

  • Sydorchuk Larysa,
  • Dzhuryak Valentina,
  • Sydorchuk Andrii,
  • Levytska Svitlana,
  • Petrynych Volodymyr,
  • Knut Ruslan,
  • Kshanovska Anna,
  • Iftoda Oksana,
  • Tkachuk Olexii,
  • Kyfiak Petro,
  • Popovich Andrii,
  • Khomko Oleh,
  • Sydorchuk Ruslan

DOI
https://doi.org/10.2478/enr-2020-0024
Journal volume & issue
Vol. 54, no. 3
pp. 217 – 226

Abstract

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Objective. The cytochrome 11B2 aldosterone synthase gene (CYP11B2) that links to aldosterone synthase enzyme synthesis changes and blood pressure regulation is of particular interest among the renin-angiotensin-aldosterone system encoding genes.

Keywords