Effect of COVID-19 on male reproduction

Abstract

There is a structural basis for invasion of the male reproductive system by the novel coronavirus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Current evidence suggests this virus can cause substantial damage to male testicles, leading to decreased testosterone levels, increased luteinizing hormone levels, and a decrease in sperm production and quality. Potential mechanisms for this damage include local inflammation of the testes, cytokine storms and fever. SARS-CoV-2 has strong transmissive ability, and its impact on the male reproductive system deserves attention. In view of the limited existing research, the aim of this study was to review the impact of the novel coronavirus on male reproduction and the potential mechanism.

Keywords

• sars-cov-2
• male reproductive system
• male fertility
• covid-19
• reproductive hormones
• damage mechanism