Clinical manifestations of the motor function of the upper gastrointestinal tract in children with autonomic dysfunction

Abstract

We examined 109 children with autonomic dysfunction syndrome aged 6–16 years, which were divided into 2 groups. The basic group enrolled 87 children with autonomic dysfunction syndrome and impaired motor function of the upper alimentary canal; the comparison group included 22 children with autonomic dysfunction syndrome without the impaired motor function of the upper alimentary tract. The examination scheme developed by us for children observed included the collection of complaints, anamnesis of life and illness, an objective examination using clinical, instrumental, and laboratory research methods. The following information was studied: age, sex, course of pregnancy and childbirth in the mother, diseases in early childhood, the presence of chronic and functional diseases of the digestive system in parents, the presence of autonomic dysfunction in the child’s parents, the nature of nutrition in infancy and school age, the presence of food allergies and the influence of psychogenic factors, duration of complaints, frequency of exacerbations, concomitant pathology. To assess the clinical course of autonomic dysfunction and motor disorders of the upper gastrointestinal tract, the symptoms of diseases were studied taking into account the results of physical examination, general clinical study of blood and urine, a biochemical blood test, a study of feces for helminth eggs, electrocardiography, consultations of specialists (otorhinolaryngologist, neurologist, ophthalmologist), ultrasound examination of the abdominal organs. The state of the mucous membrane of the stomach, duodenum and the presence of motor-evacuation disorders in the form of reflux were assessed according to the data of fibroesophagogastroduodenoscopy, which was carried out using Richard Wolf 2163 (Germany) and Olympus CLE 10 (Japan) fiberscopes, followed by a biopsy according to the generally accepted method.

Keywords

• autonomic dysfunction
• motor function
• children