The Red Blood Cell Distribution Width–Albumin Ratio Was a Potential Prognostic Biomarker for Diabetic Ketoacidosis

Abstract

Depu Zhou, Jie Wang, Xiaokun Li Department of Endocrinology, Yanbian University Hospital, Yanji, Jilin Province, People’s Republic of ChinaCorrespondence: Xiaokun LiDepartment of Endocrinology, Yanbian University Hospital, No. 119, Shizi Street, Yanji City, Jilin Province, 133000, People’s Republic of ChinaTel [phone]Email [email protected]: The red blood cell distribution width (RDW)–albumin ratio (RA) is a new biomarker, which is d-efined as RDW divided by albumin. This study aimed at determining the prognostic values of RA for diabetic ketoacidosis (DKA).Methods: Data were obtained from Medical Information Mart for Intensive Care Database III V1.4 (MIMIC-III) and the RA calculated. Multivariate Cox regression analysis was performed to determine the correlation between RA and 90-day mortality or 365-day mortality. To further investigate the association with RA and mortality, the patients were divided into two groups. The second outcome was the association between the incidence of DKA-related infections and RA.Results: For DKA patients in the ICU, RA was significantly correlated with 90-day mortality (HR: 2.1, 95% CI: 1.5, 3.0, p

Keywords

• red blood cell distribution width - albumin ratio
• diabetic ketoacidosis
• diabetic ketoacidosis - associated infection
• all-cause mortality