Dose Impaired Relaxation of Left Ventricle Affect Early Outcomes

Abstract

Although systolic dysfunction is revealed as a prognostic factor in cardiac surgery , the role of diastolic dysfunction as a predictive factor is less evaluated. In this retrospective study from 872 patients that underwent isolated coronary artery bypass graft(Jan 2008-Feb 2009),388 patients had normal left ventricular ejection fraction (>50%). These are divided in two groups, Group 1: 361 patients without diastolic dysfunction (impaired relaxation) and Group 2: 27 patients with diastolic dysfunction ( impaired relaxation) . Mean age in group 1 was 57.72 year and in group 2 was 61.16 year (P =0.07). Risk factors such as diabetes mellitus, hypertention and dyslipidemia were similar. Although overall complication rate was higher in group 2( 11.1% vs 2.8% P value 0.05),but when each complication was studied individually no significant statistical difference was found. Also no significant statistical difference was found in mortality (2.2% in group 1 vs 7.4% in group 2 P =0.1). In conclusion, from clinical standpoint diastolic dysfunction can be an important factor in assessing surgical outcome in patients whom underwent coronary artery bypass grafting.

Keywords

• Coronary artery bypass
• heart failure
• diastole
• mortality
• complications