Nature Communications (Oct 2021)

Spared perilesional V1 activity underlies training-induced recovery of luminance detection sensitivity in cortically-blind patients

  • Antoine Barbot,
  • Anasuya Das,
  • Michael D. Melnick,
  • Matthew R. Cavanaugh,
  • Elisha P. Merriam,
  • David J. Heeger,
  • Krystel R. Huxlin

DOI
https://doi.org/10.1038/s41467-021-26345-1
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 18

Abstract

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In humans, stroke damage to V1 causes large visual field defects. Spared V1 activity prior to training predicts the amount of training-induced recovery in luminance detection sensitivity. Moreover, visual training changes population receptive field properties within residual V1 circuits.