Sleep Science (Mar 2014)

The use of citalopram for the treatment of cataplexy

  • Hassana de Almeida Fonseca,
  • Danielle Antunes Lopes,
  • Danielle Pereira,
  • Danilo Anunciatto Sguillar,
  • Eduardo Lopes,
  • Nilce Sanny Costa da Silva Behrens,
  • Taís Figueiredo de Araújo Lima,
  • Marcia Pradella-Hallinan,
  • Juliana Castro,
  • Sergio Tufik,
  • Fernando Morgadinho Santos Coelho

DOI
https://doi.org/10.1016/j.slsci.2014.07.016
Journal volume & issue
Vol. 7, no. 1
pp. 50 – 52

Abstract

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This is a series of cases describing the use of citalopram for the treatment of cataplexy in patients with narcolepsy. Cataplexy is the most specific symptom of narcolepsy, being characterized by a sudden and temporary loss of muscle tonus, triggered by episodes of emotion during vigil. Some antidepressants, besides gamma-hydroxybutyrate, are used for the control of cataplexy. As gamma-hydroxybutyrate is not available in Brazil, local treatment is usually done by the use of antidepressants. Citalopram is a selective inhibitor of serotonin reuptake, with reasonable price and with fewer side effects when compared with other drugs of the same type. In this study, we report a series of cases with patients with narcolepsy and cataplexy, treated with citalopram for the control of cataplexy.

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