Nature Communications (Feb 2023)

Molecular imaging of liver inflammation using an anti-VCAM-1 nanobody

  • Maxime Nachit,
  • Christopher Montemagno,
  • Romain Clerc,
  • Mitra Ahmadi,
  • François Briand,
  • Sandrine Bacot,
  • Nick Devoogdt,
  • Cindy Serdjebi,
  • Catherine Ghezzi,
  • Thierry Sulpice,
  • Alexis Broisat,
  • Isabelle A. Leclercq,
  • Pascale Perret

DOI
https://doi.org/10.1038/s41467-023-36776-7
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 12

Abstract

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Here, the authors present a noninvasive tool to detect liver inflammation using nuclear imaging, as an alternative to biopsy. The prove the diagnostic power of this tool to detect liver inflammation in preclinical models of chronic liver disease.